Crews were hard at work Wednesday morning clearing the stage for a train derailment near Craven, Sask., About 30 miles northwest of Regina.
A CP Rail train with potassium chloride derailed Tuesday night just south of the village, where the rails cross Highway 20.
In a statement, CP Rail said there were no injuries and no concerns about public safety.
Pictures posted by the village and others on social media show railway cars with serious damage.
In a Facebook post, the Village of Craven asked people to avoid the area to allow emergency crews to work.
CP said it immediately sent crew and resources to the scene Tuesday night.
From Wednesday morning, work was underway to clean up the site of the derailment.
Members of the fire department in Lumsden were also on the scene Tuesday.
Highway 20 in Craven remained blocked Wednesday morning.
Village officials directed travelers to or from Regina to use Highway 99 or Highway 6 as an alternative route.
There are no words on the cause of the derailment.
Craven has a population of about 210. The village is best known as the site of the annual Country Thunder music festival.